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Tri(Hydroxymethyl) Amino Methane Hydrochloride, ≥99.0%

Product Numbers: K687002

Product name: Tri(Hydroxymethyl) Amino Methane Hydrochloride

English name: Tri(Hydroxymethyl) Amino Methane Hydrochloride

Alias: Tris(hydroxymethyl)aminoethane hydrochloride; Tris(hydroxymethyl)aminomethane hydrochloride; 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL, HYDROCHLORIDE; SPECTRIS(R) HYDROCHLORIDE; SPECTRIS(TM) HYDROCHLORIDE; MOLE-READY- TRIS; 1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride; 3-propanediol,2-amino-2-(hydroxymethyl)-hydrochloride; trizmahydrochloride(trishydrochloride); 2-amino-2-(hydroxymethyl )propane-1,3-diol hydrochloride (1:1); 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, chloride

CAS Number: 1185-53-1

Molecular formula: C₄H₁₂ClNO₃

Molecular mass: 157.6

EINECS number: 214-684-5

Trometamol hydrochloride properties:

Melting point: 150-152°C

Density: 1.05g/mLat20°C

Storage conditions: StoreatRT.

Solubility: H₂O: 4Mat20°C, clear, colorless

Form: crystalline

Color: clearcolorless(40%(w/w)inH₂O)solution

PH value: 2.5-4.0 (25℃, 4MinH₂O)

PH range of acid-base indicator discoloration: 7.0-9.0

Acidity coefficient (pKa): 8.1(at25℃)

Water solubility: SOLUBLE

λ:260nmAmax:0.12

λ:280nmAChemicalbookmax:0.08

Sensitivity Hygroscopic

BRN3675235

stability:

Stable.Incompatiblewithstrongoxidizingagents,bases,moisture.InChIKey:QKNYBSVHEMOAJP-UHFFFAOYSA-N

CAS database: 1185-53-1 (CASDataBaseReference)

EPA chemical substance information: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1185-53-1)

Introduction: Trometamol hydrochloride is referred to as Tris-HCl. Trometamol hydrochloride buffer (Tris-HCl buffer) is not only widely used as a solvent for nucleic acids and proteins, but also has many important uses

Application: Tris-HCl is used for protein crystal growth under different pH conditions. The low ionic strength of Tris-HCL buffer can be used to form the intermediate fiber of C.elegans lamin. Tris-HCl is also one of the main components of protein running buffer. In addition, Tris-HCL is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Tris-HCl is also used as a titration standard.

Uses: The pH of all buffers depends on temperature and concentration. For Tris buffer, the pH increases by approximately 0.03 units for every 1°C increase in temperature, and the pH decreases by 0.03-0.05 units for every 10-fold dilution.

For biological buffer

Used as an intermediate in organic synthesis

Security Information:

Dangerous goods mark: Xi

Hazard category code: 36/37/38

Safety Instructions 26-36

WGK Germany :3

RTECS number: TY2900000

F :3

TSCA: Yes

Customs code: 29221980